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Eukaryotic PFAS, sometimes designated large-PurL, is a single peptide chain that carries functional domains equivalent to a multienzyme cascade consisting of small-PurL, PurQ, and PurS in Gram-positive bacteria (Schendel et al., 1989

Vid24p, a novel protein localized to the fructose-1, 6-bisphosphatase-containing vesicles, regulates targeting of fructose-1,6-bisphosphatase from the vesicles to the vacuole for degradation