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Description
( Bmal1 (one of the essential clock genes that participate in the maintenance of the circadian periodicity at the cellular level) in mice suprachiasmatic nucleus (SCN) led to increased escape latencies and number of escape failures in the learned helplessness paradigm, induced higher immobility time in the tail suspension test, and decreased the time spent in the light compartment of the light/dark test

Early research, mostly done on different groups of older mice, found that FOXO4-DRI can help heal tissues, make organs work better, and reduce inflammation related to aging (6)

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To date, no large-scale human clinical trials have confirmed that Epitalon extends lifespan or healthspan in people

Researchers posit that the peptide appears to regulate various cellular processes primarily by controlling the production of two compounds: Vascular Endothelial Growth Factor (VEGF) and Transforming Growth Factor beta (TGF-B)

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