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Interestingly, a placebo-controlled study (6) has shown that substantial elevations (~20%) of muscle carnitine content do occur in humans following prolonged daily supplementation with carnitine tartrate when carbohydrate is ingested at the same time

In addition to maintaining the GR in the cytosol, the multiprotein complex facilitates high affinity ligand binding
PMC 5830209

mTOR is an important molecule inhibiting autophagy pathway, which remarkably elevates in the myocardium of diabetic rats leading to the occurrence of both cardiomyopathy and cardiac hypertrophy [74]

Sawicka AK, Renzi G, Olek RA. The bright and the dark sides of L-carnitine supplementation: a systematic review. J Int Soc Sports Nutr. 2020 Sep 21;17(1):49. doi: 10.1186/s12970-020-00377-2. PMID: 32958033; PMCID: PMC7507632
