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Description
533 Metformin also modulates immune responses in lupus and RA

Observed effects in human trials Reported adverse events across the IV and oral trials included headache, fatigue, dizziness, nasopharyngitis, diarrhea, flatulence, increased appetite, nausea, and back pain

Consistency matters more than perfection

Important Administration Tips Begin on a small dose and observe reaction
193,285-287 Intriguingly, emerging evidence also implicates, directly or indirectly, both GABA (see the Future research priorities section) and 5-HT 288-291 in the beneficial effects of certain dietary interventions

Cells maintain a high-NADPH/NADP + ratio
