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Description
Soluble UA can reduce the number of monocytes positive for pro-inflammatory cytokines IL-6 and TNF-alpha 35
The Nrf2 antioxidant defense system regulates cell apoptosis, senescence, extracellular matrix (ECM) metabolism, the inflammatory response of the nucleus pulposus (NP), and calcification of the cartilaginous endplates (EP) in IDD
& Cosstick, R
The mechanism is straightforward
( A ) Comparison of the effect sizes in the tissue-sharing and tissue-specific groups, with x axis illustrating the MR regulatory types, and y axis showing the absolute value of the effect size
doi: 10.1016/S0031-3955(05)70167-X
