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A PubMed Central-hosted review of peptide-based obesity treatments describes "nausea, vomiting and loss of appetite" as common effects of the GLP-1 drug class (pmc.ncbi.nlm.nih.gov)

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doi: 10.1016/0016-5085(79)90002-7

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Research demonstrates that collagen peptides working through TGF-/Smad3 pathway activation can reduce MMP-3, MMP-13, MMP-2, and MMP-9 activity while increasing procollagen synthesis, attenuating the collagen degradation characteristic of photoaged skin