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Initially focused on demographics and clinical parameters, newer studies have included a high percentage of laboratory and imaging data to reduce bias

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From the immediate ligation period, the increased intracranial (superior sagittal sinus) hypertension coincided with a consistently swollen brain, severe brain edema and congestion, large intracerebral hemorrhage in the fronto-parietal area, and intraventricular hemorrhage in the central and lateral ventricles