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Most claims are based on lab data, not real clinical trials with humans
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Autophagy in many instances does not require the complete cessation of food intake (protocols are available at accessed on 15 April 2023)

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Stifano G, Affandi AJ, Mathes AL, Rice LM, Nakerakanti S, Nazari B, Lee J, Christmann RB, Lafyatis R (2014) Chronic Toll-like receptor 4 stimulation in skin induces inflammation, macrophage activation, transforming growth factor beta signature gene expression, and fibrosis
