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MaennerMJShawKABaioJPatrickMDiRienzoMChristensenDLet al

Metabolic modulation via mTOR pathway and anti-angiogenesis remodels tumor microenvironment using PD-L1-targeting codelivery

Specifically, EGCG inhibits the phosphorylation of the 705th tyrosine residue of STAT, and protein kinase C delta (PKC-delta), effectively blocking STAT1 activity

The enzyme glutathione reductase, which requires NADPH as a cofactor, recycles GSSG back to GSH, maintaining this ratio [2]

site-directed mutagenesis was performed using PrimeStar Max (Takara)
