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Age-related structural and functional vascular changes are caused by cyclic stress (repeated cardiac contractions cause hemodynamic pressure changes with the greatest impact on the heart near large arteries and pulsatile and circumferential stress)

Glutathione acts as a localized "clean-up crew," helping to protect the delicate tissues of the digestive system

doi: 10.3389/fncel.2020.591874 194 HelmuthTBKumariRPalsaKNeelyEBSlagle-WebbBSimonSDet al

The results of the study also indicated that pyomelanin has strong DPPH radical-scavenging, radioprotective, anticancer, and antibacterial activities

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10.1111/j.1468-3083.2009.03295.x 179 PakpayatN.NielloudF.FortunR.Tourne-PeteilhC.VillarrealA.GrilloI.et al (2009)