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The modified amino acid, 4-hydroxyproline, is metabolized to glyoxylate and pyruvate via the action of 4-hydroxy-2-oxoglutarate aldolase 1 (encoded by the HOGA1 gene)

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Miki K, Urita Y, Ishikawa F, Iino T, Shibahara-Sone H, Akahoshi R,

Standard reconstitution involves adding 2 mL of bacteriostatic water to a 5 mg vial, yielding a concentration of 2.5 mg/mL (2,500 mcg/mL)

Mir-15a and mir-16-1 cluster functions in human leukemia

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