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B12 is used to recycle homocysteine
PLoS ONE 10:e0136468 [DOI] [PMC free article] [PubMed] [Google Scholar] Zhao X et al (2019) Benefits of vitamins in the treatment of Parkinsons disease

Low levels of these vitamins can lead to anemia, fatigue, and other symptoms, and supplementation may be necessary to correct deficiencies

Prehistoric Irrigation Systems in the Salt River Valley, Arizona. Science 214 (October 23, 1981): 4089

To get that certification, a manufacturer has to have the material tested