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The chemistry of reactive oxygen species (ROS) revisited: outlining their role in biological macromolecules (DNA, lipids and proteins) and induced pathologies

Thomas T, Stefanoni D, Reisz JA, Nemkov T, Bertolone L, Francis RO, et al

The TP53 apoptotic network is a primary mediator of resistance to BCL2 inhibition in AML cells

In the lorcaserin group, 22.6% of patients lost at least 10% of their body weight, as compared to 9.7% of patients in the placebo group [84]

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They increase the expression of beta-adrenergic receptors, leading to enhanced cardiac output