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Novel nanoparticle-based systems have shown promise for dermal delivery due to their ability to enhance drug permeation across the SC, which is naturally not permeable to a range of substances, as skin acts as a natural physical barrier to particle penetration

doi: 10.1002/ana.10828

Biomolecules 13 (4), 695

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This polymorphism is in intron 13 of the MAO-B gene and is thought to disrupt monoamine metabolism, leading to increased ROS production and oxidative stress within the central nervous system (Table 1 provides a gist of the mechanisms by which genetic polymorphisms influence prooxidant genes

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