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In Human, L-carnitine concentration in muscles is around 3 and 6 mol of per gram making muscle the major reservoir for L-carnitine in the body, however, it has been shown that L-carnitine present in the muscle does exchange easily with the plasma and muscle is unable to synthesize carnitine and relies on L-carnitine synthesized elsewhere in the body or from the dietary carnitine

Corti et al., 3.5)

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Carnitine biosynthesis in Neurospora crassa : identification of a cDNA coding for - N -trimethyllysine hydroxylase and its functional expression in Saccharomyces cerevisiae

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In addition, it acts as an activator of the urea cycle and has been proposed as a potential treatment for hyperammonemia secondary to organic acidemia, hepatic encephalopathy and even valproic acid associated hyperammonemia [46, 47]