glutathione pathway and acetaminophen 5-Oxoprolinuria as a Cause for Metabolic Acidosis Acetaminophen Toxicity: How Genetic Susceptibility
Description
The initial step required for the glucose-independent fueling of OXPHOS is the conversion of glutamine to glutamate

Schink B
It also prevents megaloblastic anemia, fatigue, and numbness or tingling in the hands and feet

Chaker L, Baumgartner C, den Elzen WP, et al
A deficiency can also result from not getting enough B12 in what you eat due to various food restrictions

In many COVID-19 cases, the virus-induced HMRD may not reset or revert even after patient discharge as virus-free (RT-PCR negative) survivors
