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214217 Additionally, sensory neurons in the dorsal root ganglia (DRG) exhibit altered phenotypes, such as reduced neurofilament synthesis, endoplasmic reticulum stress, and changes in key plasticity molecules, such as growth-associated protein 43 (GAP43) and heat shock proteins, leading to mitochondrial dysfunction and loss of peripheral nerve function

[48] So although increased exercise performance might not be behind GBB's ability to increase sweat, increased sweating is itself potentially beneficial for your health

The Wall et al

Several nutritional interventions support neuronal energy metabolism independent of hormones

- Occasionally it can cause abdominal pain and gastrointestinal disturbances

The authors of the 2025 study from the University of Turin suggest that the combination of L-carnitine and selenium may have a synergistic effect, and that L-carnitine may also have an immunomodulatory role, and its actions are not limited to peripheral thyroid hormone antagonism