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Dux activates metabolism-lactylation-MET network during early iPSC reprogramming with Brg1 as the histone lactylation reader

All species generate NADPH intracellularly, which fuels disulfide reductase systems Mammals have an NADPH-independent disulfide reductase system fueled by methionine Transsulfuation reversal allows Met-fueled reductase system yet makes Met essential Transsulfuration reversal and a Se- dependent TrxR family co-evolved with metazoans Metazoan selenoprotein TrxR1 and transsulfuration each support redox signaling Acknowledgments Funding to the authors came from the US National Institutes of Health (AG055022 and CA215784)

Umminger BL (1977) Relation of whole blood sugar concentration in vertebrate to standard metabolic rate

10.1183/16000617.0196-2021 28 CarlinA

References Padmanabhan, V., Cardoso, R

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