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Bone health: Sermorelin therapy can significantly increase bone density, thereby enhancing skeletal strength

Based on preclinical (animal and cellular) data only, inhibition of NNMT by 5-Amino-1MQ is theorised to: Raise intracellular NAD+ levels Activate SIRT1 and other sirtuins (proteins linked to metabolic regulation) Reduce fat cell (adipocyte) size and proliferation Improve insulin sensitivity These effects have been demonstrated in mouse models (Neelakantan et al., 2019), but robust human clinical trial data are currently absent

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West AC, Bechtold DA (2015) The cost of circadian desynchrony: evidence, insights and open questions

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