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Studies show benefits in models of cognitive impairment, muscle aging, atherosclerosis, osteoarthritis, diabetes, and glaucoma

Melatonin and dipeptidyl peptidase IV inhibitors (DPP-4i) are known to possess powerful antioxidant and anti-inflammatory properties and have garnered significant attention in the recent years

Knee injections are a great alternative to more invasive procedures, like surgery, and can also be used alongside other knee pain treatment options like rehabilitative therapy, hydrotherapy, and exercise therapy

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doi: 10.1016/j.ijid.2020.03.017

The sample size was estimated according to a preliminary experiment with an expected effect size of 1.0 and a low dropout rate, yielding a minimum of 18 participants per group to achieve 80% power with an alpha level of 0.05