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As a result of the fact that at least some of the glutamate generated in the PAG reaction may be released directly into the cytosol (17) GABA can be formed either directly from glutamate in the cytosol or from glutamate originating from -ketoglutarate produced in the TCA cycle from oxidatively deaminated glutamate involving GDH

To determine the role of Pol in shaping mutational landscapes across different organs, we comprehensively assessed somatic mutations across a panel of mammalian tissues

DJ-1 mutant flies show altered redox homeostasis as evidenced by high levels of global ROS and hydrogen peroxide production and decreased activity of catalase and superoxide dismutase [99]

In humans, blood levels of ergothioneine start declining linearly with the age after 60 years (75)

Surviving sepsis campaign guidelines for management of severe sepsis and septic shock
