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Tumour-initiating cells: challenges and opportunities for anticancer drug discovery

Modulating level control (Figure 8.3.2) The final control element may be a valve that is adjusted to a point between fully open and fully closed, as a function of the level being monitored

37 However, exogenous cholesterol treatment is not enough to regulate the lethality of RSL3 in human cancer cells

Competing Interest The authors declare no competing interests

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They have been approved by the FDA for diabetes treatment and weight management