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The intracellular N-terminal domain of AE1 binds to several glycolytic enzymes including PFK-1, aldolase A, and glyceraldehyde-3-phosphate dehydrogenase

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As a result, CuII(atsm) improves motor performance and cognitive function in PD models, including MPTP- and 6-OHDA-induced mice as well as transgenic mice overexpressing the human A53T -syn mutation (242)

Although HSPs were initially identified for their role in thermotolerance, they were later found to be involved in various abiotic stress responses and normal plant developmental processes [318]

*Correspondence: Yong-Yu Yang, [email protected] This article was submitted to Diabetes: Molecular Mechanisms, a section of the journal Frontiers in Endocrinology Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers