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Description
Originally created as a lipolytic compound for treating obesity, AOD-9604 has demonstrated potential in animal studies for treating heart disease, osteoarthritis, and metabolic syndrome by promoting cartilage repair and fat breakdown while inhibiting fat creation

Problems show up when you use high doses or IV forms

Clinical Indications and Who May Benefit Based on the preclinical literature and emerging clinical use patterns, BPC-157 is most commonly applied in the following areas: Tendon, ligament, and muscle injuries (sprains, partial tears, chronic tendinopathy) Post-surgical tissue healing and recovery acceleration Inflammatory bowel conditions (Crohns, ulcerative colitis, leaky gut syndromes) NSAID-induced gastric damage notably, BPC-157 counteracts aspirin- and ibuprofen-driven mucosal injury Neuropathy and nerve regeneration protocols Systemic inflammation and autoimmune flares Recovery from alcohol-related liver and gut damage It is also increasingly used as a component in broader peptide therapy protocols alongside BPC-157s companion compounds
Whenever any abnormal foreign pathogen is detected or any foreign endogenous nucleic acid is identified, pattern recognition receptors in dendritic cells and other innate immune cells recognize so-called damage-associated molecular patterns (DAMPs) and pathogen-associated molecular patterns (PAMPs), which further lead to a cascade of signaling mechanisms that, in turn, activate various immune genes, including compositions such as inflammatory cytokines and chemokines, one of the key ones being that of IFN-I (193)

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Were talking 80-95% absorption versus maybe 40-60% for nasal sprays and even less for basic oral formulations
