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Mitochondrial damage in muscle specific PolG mutant mice activates the integrated stress response and disrupts the mitochondrial folate cycle

Kang E, Wu J, Gutierrez NM et al

Acetyl-L-carnitine may also be helpful in providing neuroprotection by supporting brain energy metabolism

L-carnitine us given intravenously (by IV) to increase L-carnitine levels in people whose natural level of L-carnitine is too low because they have a genetic disorder, are taking certain drugs (valproic acid for seizures), or because they are undergoing a medical procedure (hemodialysis for kidney disease) that uses up the body's L-carnitine

[PubMed] [Google Scholar] 45.Natali A., Santoro D., Brandi L.S., Faraggiana D., Ciociaro D., Pecori N., Buzzigoli G., Ferrannini E

[DOI] [PMC free article] [PubMed] [Google Scholar] 180.Pitarch-Castellano I., Ibez-Albert E., ungo-Garzn N.C., Vzquez-Costa J.F., Sevilla T