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Interestingly, the probiotic treatment prevented several of the bone pathologies of T1D including marrow adiposity, suprpressed Wnt10b expression and suppressed osteoblast activity [149]

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Advancements in multi-omics approaches, especially probiogenomics, will provide a deeper understanding of the mechanisms behind probiotic functionality, allowing for personalized and targeted probiotic therapies

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In the future, more efforts should be made to elucidate the mechanisms underlying the role of intratumoral microbiomes in tumor development

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