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Our laboratory has offered evidence that AngIV, and AngIV analogs, are capable of facilitating HGF/c-Met activity (133)

Incubation of senescent and control IMR90 with increasing concentrations of FOXO4-DRI showed FOXO4-DRI to potently and selectively (11.73 fold difference) reduce the viability of senescent vs

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Interventions targeting biological aging offer the possibility of disrupting a foundational cause of AD

doi: 10.1186/s13023-022-02453-z

297 Apart from being an antidiabetic drug, metformin was found to effectively benefit gut epithelium by suppressing inflammation and improving ileal epithelial barrier function in interleukin-10-deficient mice, probably through AMPK activation