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The following symptoms may indicate a B12 deficiency: Signs of anaemia such as pallor, tiredness, palpitations Skin and mucous membrane changes such as glossitis (inflammation of the tongue), smooth red tongue, tongue burning [7] and hyperpigmentation of the skin Neurological symptoms: Tingling in arms and legs (paraesthesia) to numbness, dizziness, depression, forgetfulness, unsteadiness in gait, listlessness to psychosis and paralysis Why do you get nerve and leg pain with a vitamin B12 deficiency

Amylin Receptor Activation Amylin receptors are heterodimeric complexes formed by the calcitonin receptor (CTR) paired with receptor activity-modifying proteins (RAMPs)