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Moreover, although preclinical studies support the efficacy of anti-inflammatory interventions in ameliorating epilepsy and comorbid depression, clinical trial results remain heterogeneous, suggesting that inflammation suppression alone may be insufficient to fully control disease progression

*Correspondence: Anna Bogdanova, Vetsuisse Faculty, Zurich Center for Integrative Human Physiology (ZIHP), Institute of Veterinary Physiology, University of Zurich, Winterthurerstrasse 260, CH-8057 Zurich, Switzerland e-mail: [email protected] This article was submitted to Membrane Physiology and Membrane Biophysics, a section of the journal Frontiers in Physiology