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These networks play a crucial role in the reprogramming of glutamine metabolism, which in turn affects various hallmarks of cancer, including cancer cell proliferation, ROS-mediated inhibition of apoptosis, and EMT-associated invasive metastasis

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doi: 10.1111/j.1749-6632.1963.tb16647.x

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One of these pathways is pivotal route of PI3K/Akt cascade, as is an obvious regulatory mechanism for cell survival, proliferation, and metabolism [55], which is directly stimulated via FSHR, after directly interacting with adapter proteins of 14-3-3 [56]

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