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The next studies revealed particular relationships with sphincter function [197], free-radical-induced injuries [197], bleeding [144,187,192], non-specific and specific NSAID-induced lesions [201], general anesthesia (thiopental) [202] and local anesthesia (lidocaine) [203] induced disturbances, and rat models that resemble schizophrenia-positive symptoms and negative symptoms [171,200]

If a specific protocol describes an IM route, the differences from SubQ are meaningful: Longer, larger needle to reach muscle (well beyond the 8 mm SubQ needle)

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Also, people with busy lifestyles, digestive issues or absorbtion challenges may also be excellent candidates for vitamin shots