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Men with metabolic syndrome, characterized by elevated waist circumference, triglycerides, blood pressure, and fasting glucose alongside low HDL cholesterol, often see improvements across multiple parameters simultaneously

The Met ligand, HGF, which is secreted by cells in the surrounding tumor microenvironment in a paracrine manner (26) is overexpressed in about 50% of head and neck squamous cell carcinoma (HNSCC)-associated stroma (8, 25)

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