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Description
However, the relationship between tinnitus and central gain remains debated (Sedley, 2019
Dysfunction of adipocytes and chronic inflammation Studies show hypertrophic and hypoxic adipocytes in obese rats cause mitochondrial dysfunction and ROS production, while reduced antioxidant enzyme activity exacerbates OS [72]

doi: 10.1007/s11540-023-09687-9

These are unstable molecules that can cause oxidative stress, a type of cellular "rusting" that occurs as we age or face environmental toxins
presented a case series on three adolescents who developed redness on the dorsal thenar spaces of both hands while being on doxycycline, coining the term heart sign given the shape of the affected areas when the hands are placed adjacent to one another [129]
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Specific peptides can be immunomodulatory
