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doi: 10.1186/1471-2229-8-22

13.3.3 Undesirable metabolic events A key safety concern is the potential of probiotics, particularly those closely related to pathogenic species, to serve as vectors for horizontal transfer of antibiotic resistance genes to indigenous gut microorganisms

Research teams that assume 'endogenous molecule = safe to combine' are ignoring receptor affinity data and downstream signaling cascades that create risk independent of molecular origin

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Chen YP, Chen CT, Liu TP, Chien FC, Wu SH, Chen P, Mou CY
doi:10.4103/1673-5374.320969
