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Bardiot, Andreas jekle, lawrence M

Without this ISC, its enzymatic activity is compromised

BAP1 regulates IP3R3-mediated Ca2+ flux to mitochondria suppressing cell transformation

Cells invest heavily in regulating polyamine homeostasis through an elaborate feedback network involving biosynthesis, catabolism, and transport (Figure 1B)

Enhanced anti-cancer effect of artemisinin- and curcumin-loaded niosomal nanoparticles against human colon cancer cells

This reduction is often caused by oncogenic mutations in metabolic enzymes like succinate dehydrogenase (SDH), fumarase (FH), and isocitrate dehydrogenase (IDH1/2), leading to the accumulation of metabolites such as fumarate, succinate, and 2-hydroxyglutarate (2HG), respectively (reviewed in refs