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Finally, a large proportion of the other studies reviewed herein, including the ones focused on exercise, did not include or report on mitochondrial readouts following NAD + modulation

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No dose-ranging studies have established safety margins, optimal administration routes, or duration of treatment

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The metabolic effects of the compound could potentially interact with disease processes or medications in unpredictable ways

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The major proglucagon fragment is identified as the carboxy-terminal portion of proglucagon that contains 2 glucagon-related sequences [12]

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