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Methods We analyzed the metabolic profile of the skn-1-knockdown worms with nuclear magnetic resonance (NMR) spectroscopy and liquid chromatography-tandem mass spectrometry (LCMS/MS) and obtained distinctive metabolomic profiles compared to WT worms

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COA documentation where available

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Novus Biologicals Reduced Glutathione/GSH Assay Kit (Colorimetric) from Novus Biologicals&trade

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However, tags provide a bit of a shortcut as the reagents used to perform these experiments with protein tags are already well validated and widely used

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Helps maintain sterility after vial opening

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Additionally, a histological evaluation of the tissue samples was performed

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