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Following the inhibition of ceramide biosynthesis, several mechanisms would be correlated with oxidative stress and apoptosis due to immunolocalization of the lower doses of FB 1 in specific targets, such as mitochondria and nucleus (Figure 1) (101)
10.1038/nri3041 Nat Rev Immunol
& Verghese, K
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This enzyme is essential for the metabolism of methionine, folate, and RNA, as well as for the production of proteins, DNA, and RNA
doi: 10.3748/WJG.V9.I6.1307 319 TrivediPPJenaGB
