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Aging 25 , 311314 (2004)

[DOI] [PMC free article] [PubMed] [Google Scholar] 114.Donia T., Khamis A

Preclinical evidence supports that combining KRAS G12C inhibitors with CDK4/6 inhibitors could yield synergistic antitumor effects in NSCLC, colorectal, pancreatic, and oesophagal cancers, particularly when cell cycle control is compromised due to CDKN2A/B deletion or p16 inactivation [53,54]

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