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It is beginning to emerge that FSHR action requires obligatory PI3K/Akt signaling, and achieves this by supporting IGF-IGFR stimulation of Akt
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Rucki AA, Xiao Q, Muth S, Chen J, Che X, Kleponis J, et al
This equilibrium transcends biochemical necessity and is a crucial factor for the survival of the bacterium against environmental and host-induced stresses [29]

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