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These modifications can change the conformation of proteins, resulting in dysfunction and the accumulation of misfolded proteins in the cytoplasm, which are implicated in cellular aging, apoptosis, and necrosis 89

When to Seek Medical Advice About Palpitations See your GP if palpitations are frequent, prolonged, or accompanied by chest pain, dizziness, or breathlessness

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The clinical characteristics for the different medication classes are separately reviewed below

(B) CFU of H

Table 2 Candidate biomarkers for cerebrospinal fluid in patients with PD