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Severe vascular and multiorgan failure (brain, heart, liver, kidney, and gastrointestinal lesions), widespread thrombosis (peripherally and centrally) severe arrhythmias, intracranial (superior sagittal sinus) hypertension, portal and caval hypertension, and aortal hypotension were aggravated

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In Hashimotos thyroiditis (HT), major sources of oxidative stress include misfolded proteins, dysbiosis and molecular mimicry, self-tolerance defects linked to AIRE gene dysfunction, and irregularities in thyroid protein folding (da Silva et al