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And yes and no, I think the body probably may reduce the production, it probably will not shut it down because keep in mind when we're comparing, because most people have been burned by, hey, if you take steroids, your body will, it'll blow up like a balloon and because the body is not able to make its own regular, its own steroid production, which is true, which is 100 percent true

With this possibility in mind, if the bladder clock shifts by 12 h but maintains downstream control, the diurnal rhythm of volume voided per micturition might also shift 12 h even if it conflicts with the central clock