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FASEB J (2002) 16(6):6079

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This finding suggest that due to defect in cPT1 and cPT2 mediated -oxidation, these long chain fatty acids are channelized to eicosanoids production to promote mitochondrial injury in the development of alcoholic fatty liver disease

Pericardiocentesis: a clinical anatomy review

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Accordingly, monitoring of total concentrations may be misleading since free concentrations may be substantially elevated in patients with hepatic disease whereas total concentrations may appear to be normal [see Boxed Warning, Contraindications (4), Warnings and Precautions (5.1)]