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In a rat model of intervertebral disc degeneration, MOTS-c injection preserved disc height (82.4% versus 58.7% in the untreated group), restored MRI signals indicating improved disc hydration, and reduced histological degeneration scores by 44% compared to untreated controls

The findings, published online July 30 in the Proceedings of the National Academy of Sciences , build on extensive animal research

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Ratio between the lowest PoD from all EpiAlveolar model readouts in Laboratory 1 and the highest exposure estimate in the lower respiratory tract

Prolactin protects retinal pigment epithelium by inhibiting sirtuin 2-dependent cell death

The results showed that SA downregulated the cytoplasmic Keap1 protein and mRNA levels and upregulated the nuclear Nrf2, HO-1 and NQO1 protein and mRNA expression levels in osteoporosis femur tissues