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Upon its accumulation and phosphorylation, HIF-1 dimerizes with HIF- (constitutively expressed nuclear proteins), enters the nucleus, and promotes the transcription of hypoxia response elements (HRE)-containing target genes involved in energy metabolism, erythropoiesis, vascular remodelling, and other processes (Fig

Complications or ultimately death arising from these infections are often associated with hyperinduction of proinflammatory cytokine production, which is also known as cytokine storm

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Centrifuge the lysate for 30 min at 10,000xg and 2-8 C

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(2018) showed that resveratrol (10mg/kg) with the NAC at a dosage of 400 mg/kg demonstrated a significant improvement in the hearing impairment induced by furosemide and kanamycin in Wistar rats