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Verification with serum methylmalonic acid and/or serum homocysteine level may be necessary in asymptomatic patients with high-risk conditions, symptomatic patients with low-normal levels of vitamin B 12 (200 to 350 pg per mL), or symptomatic patients in whom vitamin B 12 deficiency is unlikely but must be excluded

Pens are shipped with ice packs to ensure proper temperature control

PubChem compound summary for methylcobalamin

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Hcy-related enzyme SNPs in the methionine cycle were associated with efficacy

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