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This oligomerization leads to protein toxic stress, ultimately inducing cell death

Originating from Central and South America, these green fruits are now a staple in many diets around the world, including in the health-conscious circles of modern urban centers

Becaplermin is one of the only growth factors actually approved for wound healing

Placebo-controlled evaluation of four novel compounds for the treatment of schizophrenia and schizoaffective disorder

When we combined xCT overexpression with GPX4 deletion, we found that elevated Cys availability rescues GPX4-deficient cells from ferroptotic cell death (Fig

It has also been demonstrated that GSH cannot be considered only as a mere free radical scavenger but that it takes part in the network governing the choice between survival, necrosis and apoptosis as well as in altering the function of signal transduction and transcription factor molecules