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doi: 10.1371/journal.pone.0251135 149 GonzalezDEForestoRDRibeiroAB

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This dual inhibition attenuates systemic inflammation and tissue damage in SLE models ( Enhanced HDAC activity in SLE worsens immune dysregulation through the repression of anti-inflammatory genes such as Foxp3 and promotion of Th17 responses (150, 151)

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