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Pekny M, Nilsson M

33 DingN.WangA.ZhangX.WuY.WangR.CuiH.et al (2017)

Investigation of the volatile aroma components of garlic leaves essential oil

Semi-saturation mutagenesis on the conformationally flexible H241 residue shows that only H241N and H241Q retained low activity, indicating that H241 is vital for the conformation required to bind PLP and tyrosine
These phytochemicals principally interacted with pivotal neuro-inflammatory signaling waterfalls, improved brain enzymatic activity, decreased nitrosative stress and RNS formation, improved brain antioxidant defense, regulated of pro-inflammatory-related gene expression, restored the activity of astrocytes and microglial cells, modulated brain transcription factors expression, alleviated COXs expression, enhanced expression of anti-inflammatory genes, and protected brain neuronal cells (248, 401, 402)
